Immune checkpoint inhibitor (ICI) treatment has produced striking results in patients with colorectal cancer (CRC) of the subtype deficient mismatch repair (dMMR), with brief preoperative ICI treatment resulting in complete shrinkage of the tumor. However, dMMR CRC constitute 10% of all CRC diagnoses. The majority of patients have proficient MMR (pMMR) tumors, with limited effect…
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The influenza vaccine - an old friend in new territories
by Mikail Gögenur, PhD student, MDSurgery is the only treatment that today can cure patients with colorectal cancer. However, up to 30% of patients experience a relapse of their cancer following curative-intended surgery. Relapse is the leading cause of death after cancer surgery, while a surgery-induced dysfunction in the immune system is hypothesized to be…
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