immune checkpoint inhibitor Archives - Center for Surgical Science (CSS)

16/09/2022

NEYE-fonden supports a new study from Center for Surgical Science that investigates novel combination therapies, intratumoral flu vaccine and systemic immunotherapy, in patients with colorectal cancer

Immune checkpoint inhibitor (ICI) treatment has produced striking results in patients with colorectal cancer (CRC) of the subtype deficient mismatch repair (dMMR), with brief preoperative ICI treatment resulting in complete shrinkage of the tumor. However, dMMR CRC constitute 10% of all CRC diagnoses. The majority of patients have proficient MMR (pMMR) tumors, with limited effect…