Originally from China, I received my scientific education and training in the UK. Prior to joining the CSS, I had 7 years of research experience in small molecular therapeutics development and murine intestinal metabolism study. Although I have a wide range of research interests and technical expertise, my current focus is within molecular and celluar biology in the translational setting. My primary role in the CSS is the histology processing and analysis of patient derived biopsies and organoid cultures.

Dec 2018 – Feb 2020 Research Technician, Gut Signalling and Metabolism MRC LMS,

Imperial College London, UK

Oct 2010 – Sept 2016 Research Technician, Institute of Prion Diseases, MRC Prion Unit at UCL, London UK

2008 – 2009 MSc. Molecular Biology and Pathology of Viruses, Imperial College London, UK

2003 – 2007 BSc. Human Genetics, University College London, UK

In the CSS laboratory, we investigate colorectal cancer (CRC) through the analysis of biopsies and 3D patient-derived organoid (PDO) cultures. Through the use PDO, we aim to mimic the microenvironment and spatial dynamic of the tumour in patients to study its pathology and response to treatment. Histology allows us to identify different CRC subtypes and to analyze the PDO culture to confirm that it reflects true tumour morphology. The goal of the research is to develop personalized medicine for CRC sufferers, using PDO as a model to predict specific treatment outcome.

#Colorectal cancer #patient derived organoids #histology #personalized medicine