I am a medical doctor with a long-standing experience in mentoring, teaching, and project work. I have been a part of Center for Surgical Science since 2016 and have found great interest in health research and gained practical knowledge in systematic reviews, GCP-monitored clinical trials and retrospective studies. Currently, I’m full time researcher as a PhD student. My research areas are (i) the use of melatonin as an anti-inflammatory and oncostatic agent and (ii) cardiovascular complications after colorectal cancer surgery.


PhD Student at Center for Surgical Science

09/2022 – 06/2023: Teaching assistant in epidemiology, University of Copenhagen

01/2018 – 06/2022:  Instructor in Anatomy, Physiology, Pathology, and Terminology at KNORD

08/2020 – 07/2021:  Scholar student at Center for Surgical Science

08/2014 – 07/2021:  Manager at Learning Centre at Niels Brock

03/2020 – 07/2021:  Health Specialist at The Joint Danish Authorities COVID-19 Hotline

11/2014 – 07/2021:  Nursing substitute at FADL Copenhagen

08/2016 – 08/2017:  Scholar student at Center for Surgical Science

05/2009 – 06/2016:  Communication employee, Lejerbo København

2018 – 2021: M.Sc. Medicine, University of Copenhagen

2014 – 2017: B.Sc. Medicine, University of Copenhagen

2010 – 2013: Niels Brock, School of Excellence

09/2017 – 11/2017: Basic Statistics for Health Researchers (ECTS credits: 11)

  • Graduate School of Health and Medical Sciences, University of Copenhagen

05/2017: Scientific writing (ECTS credits: 5.7)

  • Centre for Perioperative Optimization, Herlev Hospital, University of Copenhagen

01/2017: Presentation of medical results (ECTS credits; 2.5)

  • Graduate School of Health and Medical Sciences, University of Copenhagen

11/2017: Global Health Case Competition at University of Copenhagen

  • My team was awarded the third prize at the Global Health Case Competition 2017, in which we had solve a case on how to improve access to reproductive and sexual healthcare to migrating women. Our solution was a post-rape treatment delivered by drones as treatment has to start within 72 hours and migration women often are difficult to reach physically.

I am currently conducting randomized controlled trials with different applications of melatonin. In one study, we are examining its ability to alleviate Low Anterior Resection Syndrome symptoms. In another study, we are examining how it affect the gene and protein expression profiles of actinic keratosis. Furthermore, I’m investigating myocardial injury and major cardiovascular event after colorectal cancer surgery and if they affect outcomes after surgery.

In my pre-graduate affiliation with CSS, my focus was to learn as much as possible and I therefore conducted research in different patient groups and used different methods and techniques. I took part in a randomized controlled trial, in which we investigated prevention of depression and improving endothelial dysfunction with melatonin in patients with acute coronary syndrome. I also conducted a retrospective cohort study investigating myocardial injury in patients after colorectal cancer surgery and a systematic review on the prevention of depression in patients with cancer.

  • Gögenur M, Balsevicius L, Bulut M, Colak N, Justesen TF, Fiehn AK, Jensen MB, Høst-Rasmussen K, Cappelen B, Gaggar S, Tajik A, Zahid JA, Bennedsen ALB, D’Ondes TDB, Raskov H, Sækmose SG, Hansen LB, Salanti A, Brix S, Gögenur I. Neoadjuvant intratumoral influenza vaccine treatment in patients with proficient mismatch repair colorectal cancer leads to increased tumor infiltration of CD8+ T cells and upregulation of PD-L1: a phase 1/2 clinical trial. J Immunother Cancer. doi: 10.1136/jitc-2023-006774. PMID: 37172969.
  • Marcucci M, Painter TW, Conen D et. al; POISE-3 Trial Investigators and Study Groups. Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery : An International Randomized Controlled Trial. Ann Intern Med. doi: 10.7326/M22-3157. PMID: 37094336.
  • Zhang DG, Zahid JA, Ali Z, Thomsen SF. Risk of Atopic Disorders in Patients with Chronic Urticaria: A Systematic Review and Meta-Analysis. Dermatology. doi: 10.1159/000525870. PMID: 36044838.
  • Devereaux PJ, Marcucci M, Painter TW et al.; POISE-3 Investigators. Tranexamic Acid in Patients Undergoing Noncardiac Surgery. N Engl J Med. doi: 10.1056/NEJMoa2201171. PMID: 35363452.
  • Zahid JA, Orhan A, Ekeloef S, Gögenur I. Myocardial Injury After Colorectal Cancer Surgery and Postoperative 90-Day Mortality and Morbidity: A Retrospective Cohort Study. Dis Colon Rectum. doi: 10.1097/DCR.0000000000002061. PMID: 34508013.
  • Vogelsang RP, Bojesen RD, Hoelmich ER, Orhan A, Buzquurz F, Cai L, Grube C, Zahid JA, Allakhverdiiev E, Raskov HH, Drakos I, Derian N, Ryan PB, Rijnbeek PR, Gögenur I. Prediction of 90-day mortality after surgery for colorectal cancer using standardized nationwide quality-assurance data. BJS Open. doi: 10.1093/bjsopen/zrab023. PMID: 33963368.
  • Zahid JA, Grummedal O, Madsen MT, Gögenur I. Prevention of depression in patients with cancer: A systematic review and meta-analysis of randomized controlled trials. J Psychiatr Res. doi: 10.1016/j.jpsychires.2019.10.009. PMID: 31655426.
  • Madsen MT, Zahid JA, Hansen CH, Grummedal O, Hansen JR, Isbrand A, Andersen UO, Andersen LJ, Taskiran M, Simonsen E, Gögenur I. The effect of melatonin on depressive symptoms and anxiety in patients after acute coronary syndrome: The MEDACIS randomized clinical trial. J Psychiatr Res.. doi: 10.1016/j.jpsychires.2019.09.014. PMID: 31586772.
  • Zahid JA, Isbrand A, Kleif J, Schou-Pedersen AV, Lykkesfeldt J, Madsen MT, Gögenur I. The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial. J Pineal Res. doi: 10.1111/jpi.12600. PMID: 31355944.


Research keywords

#Melatonin #EndothelialDysfunction #ColorectalCancerSurgery #PostoperativeComplications #LowAnteriorResectionSyndrome