{"id":9238,"date":"2020-03-22T23:27:54","date_gmt":"2020-03-22T21:27:54","guid":{"rendered":"https:\/\/centerforsurgicalscience.dk\/?page_id=9238"},"modified":"2022-04-11T13:24:37","modified_gmt":"2022-04-11T11:24:37","slug":"translational","status":"publish","type":"page","link":"https:\/\/centerforsurgicalscience.dk\/da\/translational\/","title":{"rendered":"Translationel"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"9238\" class=\"elementor elementor-9238\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d5e4395 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d5e4395\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;03f8d64&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-53e333f\" data-id=\"53e333f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c179cc8 elementor-widget elementor-widget-text-editor\" data-id=\"c179cc8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>I \u00f8jeblikket genereres der data om indsigt i de molekyl\u00e6re og cellul\u00e6re sygdomsm\u00f8nstre i et hidtil uset tempo. Men overf\u00f8rslen af resultater fra basalforskning til en forbedret patientbehandling er stadig en sv\u00e6r, men vigtig udfordring. Ved at stille kliniske sp\u00f8rgsm\u00e5l, baseret p\u00e5 resultaterne fra basalforskningen, bestr\u00e6ber vi os p\u00e5 at give kliniske svar og at udvikle nye behandlingsregimer og -strategier for at forbedre patienternes outcome. Da kirurgi stadig er vigtig for de fleste kurative behandlinger, mener vi, at den molekyl\u00e6rbiologiske forskning er lige s\u00e5 v\u00e6rdifuld for personlig kirurgi som for personlig medicin.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/p><p>Vores m\u00e5l er at overf\u00f8re de videnskabelige translationelle opdagelser til patientbehandlingen i kirurgisk onkologi og perioperativ medicin. Vores hovedfokus er patofysiologien ved perioperativ stress, og den \u00e6ndring af potentielle stressfaktorer, der ses ved kolorektalcancer. I samarbejde med etablerede kliniske forskere fremmer vi det tv\u00e6rvidenskabelige samarbejde mellem kliniske investigatorer og forskere indenfor translationel og basalforskning.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d5ae198 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d5ae198\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;_id&quot;:&quot;c30c415&quot;,&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-bba9d37\" data-id=\"bba9d37\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2cbf350 elementor-widget elementor-widget-image\" data-id=\"2cbf350\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"885\" height=\"586\" src=\"https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope-1024x678.jpeg\" class=\"attachment-large size-large wp-image-8555\" alt=\"\" srcset=\"https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope-1024x678.jpeg 1024w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope-300x199.jpeg 300w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope-768x508.jpeg 768w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope-418x277.jpeg 418w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope-400x265.jpeg 400w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope-900x596.jpeg 900w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope-453x300.jpeg 453w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope-1020x675.jpeg 1020w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope-16x12.jpeg 16w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/translational_stethoscope.jpeg 1080w\" sizes=\"(max-width: 885px) 100vw, 885px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-86eea9d\" data-id=\"86eea9d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4506b33 elementor-widget elementor-widget-testimonial\" data-id=\"4506b33\" data-element_type=\"widget\" data-widget_type=\"testimonial.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-testimonial-wrapper\">\n\t\t\t\t\t\t\t<div class=\"elementor-testimonial-content\">Vores m\u00e5l er at overf\u00f8re de videnskabelige translationelle opdagelser til patientbehandlingen i kirurgisk onkologi og perioperativ medicin.<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-testimonial-meta elementor-has-image elementor-testimonial-image-position-aside\">\n\t\t\t\t<div class=\"elementor-testimonial-meta-inner\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-testimonial-image\">\n\t\t\t\t\t\t\t<a href=\"https:\/\/centerforsurgicalscience.dk\/da\/team\/rasmus-vogelsang\/\"><img decoding=\"async\" width=\"239\" height=\"239\" src=\"https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/Rasmus-Vogelsang.jpg\" class=\"attachment-full size-full wp-image-8049\" alt=\"\" srcset=\"https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/Rasmus-Vogelsang.jpg 239w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/Rasmus-Vogelsang-150x150.jpg 150w\" sizes=\"(max-width: 239px) 100vw, 239px\" \/><\/a>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-testimonial-details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-testimonial-name\" href=\"https:\/\/centerforsurgicalscience.dk\/da\/team\/rasmus-vogelsang\/\">Rasmus Vogelsang<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-testimonial-job\" href=\"https:\/\/centerforsurgicalscience.dk\/da\/team\/rasmus-vogelsang\/\">Postdoctoral researcher<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-07a5490 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"07a5490\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;ce41001&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-42db771\" data-id=\"42db771\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-97f5f80 elementor-widget elementor-widget-text-editor\" data-id=\"97f5f80\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Den translationelle gruppe best\u00e5r af en styregruppe med professorer, ph.d.-studerende, forsknings\u00e5rsstuderende, klinikere og basalforskere indenfor translationel forskning. Gruppen underst\u00f8tter forskere og klinikere fra de tidlige planl\u00e6gningsstadier af konceptudvikling, design, analyseplan og budget til udf\u00f8relse, dataanalyse, datarapportering og klinisk implementering. Vi har tv\u00e6rvidenskabelige samarbejder med nationale og internationale forskningsgrupper, hvor vi tester basale forskningsresultater for deres kliniske effekt og anvendelighed. Vores translationelle studier omhandler de f\u00f8rste kliniske fors\u00f8g, proof of concept-studier, og testning af nye interventioner i tidlige fors\u00f8g, for at danne grundlaget for anvendelse og implementering i klinikken, og det perioperative forl\u00f8b.<\/p><p>Via hospitalets egne laboratorier og eksterne forskningslaboratorier kan vi rekvirere analyser og bioinformatik. Vores translationelle laboratorieforskning fokuserer p\u00e5 \u00e6ndringer i genekspressionsprofiler, \u00e6ndringer i cytokinprofiler, celleadh\u00e6sion og -migration, dynamiske \u00e6ndringer i tumormikromilj\u00f8et og forandringer i tarmmikrobiomet.\u00a0\u00a0 \u00a0\u00a0<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0b9fbac elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0b9fbac\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;52d2994&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-b218984\" data-id=\"b218984\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f56f6d1 elementor-widget elementor-widget-heading\" data-id=\"f56f6d1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Samarbejdspartnere<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-11216b6\" data-id=\"11216b6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9e5153f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9e5153f\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;b6ae082&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-b8a2fd6\" data-id=\"b8a2fd6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1e548e3 elementor-widget elementor-widget-eael-feature-list\" data-id=\"1e548e3\" data-element_type=\"widget\" data-widget_type=\"eael-feature-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"-icon-position-left -tablet-icon-position-left -mobile-icon-position-left\">\n\t\t\t<ul id=\"eael-feature-list-1e548e3\" class=\"eael-feature-list-items circle stacked\">\n\t\t\t                <li class=\"eael-feature-list-item elementor-repeater-item-9467448\">\n                    \n\t\t\t\t\t\t<div class=\"eael-feature-list-icon-box\">\n\t\t\t\t\t\t\t<div class=\"eael-feature-list-icon-inner\">\n\n\t\t\t\t\t\t\t\t<a class=\"eael-feature-list-icon fl-icon-0\"href=\"https:\/\/ruc.dk\/en\/research-group\/molecular-and-medical-biology\" target=\"_blank\">\n\n\t\t<i aria-hidden=\"true\" class=\"fas fa-university\"><\/i>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"eael-feature-list-content-box\">\n\t\t\t\t\t\t\t<h3 class=\"eael-feature-list-title\"                            ><a href=\"https:\/\/ruc.dk\/en\/research-group\/molecular-and-medical-biology\" target=\"_blank\">Roskilde Universitet<\/a><\/h3\t\t\t\t\t\t>\n\t\t\t\t\t\t<p class=\"eael-feature-list-content\">Molekyl\u00e6r og Medicinal Biologi<\/p>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/li>\n\t\t\t\t                <li class=\"eael-feature-list-item elementor-repeater-item-4aaa243\">\n                    \n\t\t\t\t\t\t<div class=\"eael-feature-list-icon-box\">\n\t\t\t\t\t\t\t<div class=\"eael-feature-list-icon-inner\">\n\n\t\t\t\t\t\t\t\t<a class=\"eael-feature-list-icon fl-icon-1\"href=\"https:\/\/www.sund.ku.dk\/\" target=\"_blank\">\n\n\t\t<i aria-hidden=\"true\" class=\"fas fa-university\"><\/i>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"eael-feature-list-content-box\">\n\t\t\t\t\t\t\t<h3 class=\"eael-feature-list-title\"                            ><a href=\"https:\/\/www.sund.ku.dk\/\" target=\"_blank\">K\u00f8benhavns Universitet<\/a><\/h3\t\t\t\t\t\t>\n\t\t\t\t\t\t<p class=\"eael-feature-list-content\">Det Sundhedsvidenskabelige Fakultet\n<\/p>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/li>\n\t\t\t\t                <li class=\"eael-feature-list-item elementor-repeater-item-0fceaaf\">\n                    \n\t\t\t\t\t\t<div class=\"eael-feature-list-icon-box\">\n\t\t\t\t\t\t\t<div class=\"eael-feature-list-icon-inner\">\n\n\t\t\t\t\t\t\t\t<a class=\"eael-feature-list-icon fl-icon-2\"href=\"https:\/\/www.bric.ku.dk\/\" target=\"_blank\">\n\n\t\t<i aria-hidden=\"true\" class=\"fas fa-university\"><\/i>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"eael-feature-list-content-box\">\n\t\t\t\t\t\t\t<h3 class=\"eael-feature-list-title\"                            ><a href=\"https:\/\/www.bric.ku.dk\/\" target=\"_blank\">K\u00f8benhavns Universitet<\/a><\/h3\t\t\t\t\t\t>\n\t\t\t\t\t\t<p class=\"eael-feature-list-content\">Biotech Research &amp; Innovation Centre\n<\/p>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/li>\n\t\t\t\t                <li class=\"eael-feature-list-item elementor-repeater-item-b9edb4d\">\n                    \n\t\t\t\t\t\t<div class=\"eael-feature-list-icon-box\">\n\t\t\t\t\t\t\t<div class=\"eael-feature-list-icon-inner\">\n\n\t\t\t\t\t\t\t\t<a class=\"eael-feature-list-icon fl-icon-3\"href=\"https:\/\/www.en.auh.dk\/departments\/department-of-molecular-medicine-moma\/\" target=\"_blank\">\n\n\t\t<i aria-hidden=\"true\" class=\"fas fa-university\"><\/i>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"eael-feature-list-content-box\">\n\t\t\t\t\t\t\t<h3 class=\"eael-feature-list-title\"                            ><a href=\"https:\/\/www.en.auh.dk\/departments\/department-of-molecular-medicine-moma\/\" target=\"_blank\">Aarhus Universitet<\/a><\/h3\t\t\t\t\t\t>\n\t\t\t\t\t\t<p class=\"eael-feature-list-content\">Molekyl\u00e6r Medicinsk Afdeling (MOMA)<\/p>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/li>\n\t\t\t\t                <li class=\"eael-feature-list-item elementor-repeater-item-9d2b503\">\n                    \n\t\t\t\t\t\t<div class=\"eael-feature-list-icon-box\">\n\t\t\t\t\t\t\t<div class=\"eael-feature-list-icon-inner\">\n\n\t\t\t\t\t\t\t\t<a class=\"eael-feature-list-icon fl-icon-4\"href=\"http:\/\/www.ici.upmc.fr\/\" target=\"_blank\">\n\n\t\t<i aria-hidden=\"true\" class=\"fas fa-university\"><\/i>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"eael-feature-list-content-box\">\n\t\t\t\t\t\t\t<h3 class=\"eael-feature-list-title\"                            ><a href=\"http:\/\/www.ici.upmc.fr\/\" target=\"_blank\">INSERM<\/a><\/h3\t\t\t\t\t\t>\n\t\t\t\t\t\t<p class=\"eael-feature-list-content\">Integrative Cancer Immunology Laboratory<\/p>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/li>\n\t\t\t\t                <li class=\"eael-feature-list-item elementor-repeater-item-a13a372\">\n                    \n\t\t\t\t\t\t<div class=\"eael-feature-list-icon-box\">\n\t\t\t\t\t\t\t<div class=\"eael-feature-list-icon-inner\">\n\n\t\t\t\t\t\t\t\t<a class=\"eael-feature-list-icon fl-icon-5\"href=\"https:\/\/www.bioengineering.dtu.dk\/english\" target=\"_blank\">\n\n\t\t<i aria-hidden=\"true\" class=\"fas fa-university\"><\/i>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"eael-feature-list-content-box\">\n\t\t\t\t\t\t\t<h3 class=\"eael-feature-list-title\"                            ><a href=\"https:\/\/www.bioengineering.dtu.dk\/english\" target=\"_blank\">Danmarks Tekniske Universitet (DTU)<\/a><\/h3\t\t\t\t\t\t>\n\t\t\t\t\t\t<p class=\"eael-feature-list-content\">DTU Bioengineering<\/p>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/li>\n\t\t\t\t                <li class=\"eael-feature-list-item elementor-repeater-item-0e4987c\">\n                    \n\t\t\t\t\t\t<div class=\"eael-feature-list-icon-box\">\n\t\t\t\t\t\t\t<div class=\"eael-feature-list-icon-inner\">\n\n\t\t\t\t\t\t\t\t<a class=\"eael-feature-list-icon fl-icon-6\"href=\"https:\/\/www.petermac.org\/research\/programs\/gastrointestinal-cancer-program\" target=\"_blank\">\n\n\t\t<i aria-hidden=\"true\" class=\"far fa-hospital\"><\/i>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"eael-feature-list-content-box\">\n\t\t\t\t\t\t\t<h3 class=\"eael-feature-list-title\"                            ><a href=\"https:\/\/www.petermac.org\/research\/programs\/gastrointestinal-cancer-program\" target=\"_blank\">Peter MacCallum Cancer Centre<\/a><\/h3\t\t\t\t\t\t>\n\t\t\t\t\t\t<p class=\"eael-feature-list-content\">Gastrointestinal Cancer Program<\/p>\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<\/ul>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-bf686f4\" data-id=\"bf686f4\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c5b81f8 elementor-widget elementor-widget-image\" data-id=\"c5b81f8\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/network-400x400.png\" class=\"attachment-beclinic-thumb-m size-beclinic-thumb-m wp-image-8102\" alt=\"\" srcset=\"https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/network-400x400.png 400w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/network-150x150.png 150w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/network-270x270.png 270w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/network-512x512.png 512w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/network-286x286.png 286w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2019\/08\/network-450x450.png 450w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-76a3e0a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"76a3e0a\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;0e2cc5d&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-928be2b\" data-id=\"928be2b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8f8b0c3 elementor-widget elementor-widget-spacer\" data-id=\"8f8b0c3\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9ff23d6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9ff23d6\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;0bd1806&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a597eb6\" data-id=\"a597eb6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5c55459 elementor-widget elementor-widget-heading\" data-id=\"5c55459\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Projekter<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c28ada2 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"c28ada2\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-25b5408 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"25b5408\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;d989dd8&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3dbe36d\" data-id=\"3dbe36d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b5f3e4b elementor-widget elementor-widget-text-editor\" data-id=\"b5f3e4b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul><li><strong>INEXA &#8211;<\/strong>\u00a0<strong>Intrakorporal versus ekstrakorporal anastomose ved robot-assisteret h\u00f8jresidig hemikolektomi: et randomiseret klinisk studie<\/strong><\/li><\/ul><p><strong>Registreringsnummer<\/strong>: <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03130166\">NCT03130166<\/a><\/p><p><strong>Projektledelse:<\/strong> Niclas Dohrn, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ismail-gogenur\/\">Ismail G\u00f6genur<\/a><\/p><p><strong>Status:<\/strong> Start maj 2018, igangv\u00e6rende.<\/p><p><strong>Beskrivelse: <\/strong>Form\u00e5let med studiet er at sammenligne intra- og ekstrakorporal anastomose hos patienter, der underg\u00e5r robotassisteret h\u00f8jresidig kolektomi grundet koloncancer. Vores hypotese er, at intrakorporal anastomose forbedrer det operative forl\u00f8b med patientrelaterede fordele, s\u00e5 som at patienterne kommer sig hurtigere efter operationen. Studiet er et dobbeltblindet randomiseret fors\u00f8g med inklusion af 100 patienter.<\/p><ul><li><strong>PROMIES &#8211;<\/strong><strong>\u00a0Perioperativ pulmonal monitoring ved major akut operation<\/strong><\/li><\/ul><p><strong>Projektledelse: <\/strong><a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/jakob-burcharth\/\">Jakob Burcharth<\/a>, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/sarah-ekeloef\/\">Sarah E. Busch<\/a>, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ismail-gogenur\/\">Ismail G\u00f6genur<\/a><\/p><p><strong>Status:\u00a0<\/strong>Igangv\u00e6rende (start november 2018).<\/p><p>Form\u00e5let med studiet er at beskrive forekomsten af postoperativ hypoks\u00e6mi og korrelere det til klinisk outcome. Desuden unders\u00f8ges sammenh\u00e6ngen mellem postoperative lungekomplikationer og respiratorisk muskeldysfunktion. Patienter, der underg\u00e5r en st\u00f8rre akut abdominal operation vil blive overv\u00e5get gennem de f\u00f8rste tre postoperative dage ved brug af pulsoksimetrisensor. Desuden vurderes deres postoperative respiratoriske muskelstyrke. Postoperativ hypoks\u00e6mi er et velkendt f\u00e6nomen hos patienter, der gennemg\u00e5r planlagt abdominalkirurgi, men der er kun sparsom forskning indenfor akut opererede patienter.\u00a0\u00a0<\/p><ul><li><strong>HERMES &#8211;<\/strong>\u00a0<strong>Heart Rate Monitoring in Major Emergency Surgery (et PROMIES understudie)<\/strong><\/li><\/ul><p><strong>Projektledelse:<\/strong> <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ellen-bjerrum\/\">Ellen Bjerrum<\/a>, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ismail-gogenur\/\">Ismail G\u00f6genur<\/a><\/p><p><strong>Beskrivelse:<\/strong> Form\u00e5let med studiet er at bestemme forekomsten af postoperative atrieflimmer hos patienter, der er indlagt efter en st\u00f8rre abdominal operation, og at unders\u00f8ge, om en pr\u00e6operativ m\u00e5ling af hjerterytmen (HRV) kan bruges til at forudsige postoperative kardiovaskul\u00e6re h\u00e6ndelser. \nVed brug af en postoperativ p\u00e5sat Holter-monitor m\u00e5les EKG de f\u00f8rste tre postoperative dage.<\/p><ul><li><strong>Tyktarmskr\u00e6ft: DNA-mutationsanalyse af prim\u00e6rtumor og tilh\u00f8rende metastaser<\/strong><\/li><\/ul><p><strong>Projektledelse: <\/strong><a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/astrid-bennedsen\/\">Astrid Louise Bj\u00f8rn Bennedsen<\/a>, Susanne Eiholm, Michael Bzorek, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/tove-kirkegaard-clausen\/\">Tove Kirkeg\u00e5rd Clausen<\/a>, Thomas Vauvert Faurschou Hviid, Ismail G\u00f6genur.<\/p><p><strong>Status: <\/strong>Februar 2017. Igangv\u00e6rende.<\/p><p><strong>Beskrivelse: <\/strong>Form\u00e5let med studiet er at unders\u00f8ge sammenh\u00e6ngen mellem genmutationer i prim\u00e6rtumor og de tilh\u00f8rende lymfeknudemetastaser hos patienter med kolorektalkr\u00e6ft. Vi vil ogs\u00e5 unders\u00f8ge det kliniske outcome i forhold til niveauet af de immuninvasive mark\u00f8r PD-L1 og HLA-G, og CDX2 ved hj\u00e6lp af immunhistokemisk farvning af den invasive front i tumorv\u00e6vet. Studiet er et retrospektivt studie, udf\u00f8rt p\u00e5 arkiveret FFPE-v\u00e6v fra T3 eller T4 prim\u00e6rtumorer fra 2011 og 2012.\u00a0<\/p><ul><li><strong>MEFO &#8211;<\/strong><strong>\u00a0Pr\u00e6operativ endoskopisk behandling med fosfomycin og metronidazol hos patienter med h\u00f8jresidig colon cancer og colon adenom: et klinisk proof-of-concept-interventionsstudie.<\/strong><\/li><\/ul><p><strong>Registreringsnummer:<\/strong> <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04312360\">NCT04312360<\/a><\/p><p><strong>Projektledelse: <\/strong><a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/astrid-bennedsen\/\">Astrid Louise Bj\u00f8rn Bennedsen<\/a>, Hans Raskov, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ismail-gogenur\/\">Ismail G\u00f6genur<\/a><\/p><p><strong>Status: <\/strong>Marts 2020. Igangv\u00e6rende.<\/p><p><strong>Beskrivelse: <\/strong>Form\u00e5let med studiet er at unders\u00f8ge effekten af lokal antibiotikabehandling med fosfomycin og metronidasol p\u00e5 tumorkarakteristik og biofilm i colon p\u00e5 patienter med h\u00f8jresidig colon cancer. Studiet er et klinisk proof-of-concept interventionsstudie med inclusion af 12 patienter.<\/p><ul><li><strong>Tyktarmsadenomer hos patienter, som senere udviklede tyktarmskr\u00e6ft: mikrobiotas karakteristika \u2013 et retrospektivt studie\u201d.<\/strong><\/li><\/ul><p><strong>Projektledelse: <\/strong><a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/astrid-bennedsen\/\">Astrid Louise Bj\u00f8rn Bennedsen<\/a>, Hans Raskov, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ismail-gogenur\/\">Ismail G\u00f6genur<\/a><\/p><p><strong>Beskrivelse: <\/strong>Form\u00e5let med studiet er at unders\u00f8ge, om dannelsen af biofilm p\u00e5 adenomer i colon er associeret med udvikling af colon cancer, og om sammens\u00e6tningen af (driver-) bakterier er identiske i adenomer og tumorer i colon fra den same patient. Studiet er et retrospektivt case-control-studie, udf\u00f8rt p\u00e5 arkiveret FFPE-tumorv\u00e6v. Patienterne, der har f\u00e5et lavet en colonresektion grundet colon cancer i tidsrummet 2010-2015 og har f\u00e5et fjernet polypper i colon (polypektomi) mindst 60 m\u00e5neder f\u00f8r, vil blive 1:1 matchet med patienter, der har f\u00e5et foretaget polyptektomi, men som ikke har udviklet colon cancer.<\/p><ul><li><strong>MEDACIS &#8211;<\/strong><strong>\u00a0Effekten af melatonin p\u00e5 depression, angst, d\u00f8gnrytme og s\u00f8vn hos patienter efter en blodprop i akut koronart syndrom.<\/strong><\/li><\/ul><p><strong>Registreringsnummer: <\/strong><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02451293?term=MEDACIS&amp;rank=1\">NCT02451293<\/a><\/p><p><strong>Project mangement: <\/strong><a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/michael-tvilling-madsen\/\">Michael Tvilling Madsen<\/a>, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ismail-gogenur\/\">Ismail G\u00f6genur<\/a><\/p><p><strong>Status: <\/strong>Start: januar 16. Studiet er afsluttet i august 2019.<\/p><p><strong>Beskrivelse: <\/strong>Form\u00e5let dette fase-II studie er at unders\u00f8ge, om profylaktisk behandling med melatonin har en beskyttende effekt p\u00e5 udvikling af depressive symptomer, angst, s\u00f8vn og d\u00f8gnforstyrrelser efter akut koronart syndrom. Studiet er et fase-II randomiseret studiet med inklusion af 252 patienter til enten 25 mg melatonin eller placebo 1 time f\u00f8r sengetid i 12 uger.<\/p><ul><li><strong>S\u00f8vn og d\u00f8gnrytme i den perioperative periode hos patienter indlagt til operation for tarmkr\u00e6ft: et observationelt studie.<\/strong><\/li><\/ul><p><strong>Registreringsnummer:<\/strong> <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03254836?term=Sleep+and+Survival+in+Colorectal+Cancer&amp;rank=1\">NCT03254836<\/a><\/p><p><strong>Projektledelse:<\/strong> <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/michael-tvilling-madsen\/\">Michael Tvilling Madsen<\/a>, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ismail-gogenur\/\">Ismail G\u00f6genur<\/a><\/p><p><strong>Status: <\/strong>\u00a0Start: marts 2017. Igangv\u00e6rende.<\/p><p><strong>Beskrivelse:<\/strong> Form\u00e5let med studiet er at unders\u00f8ge effekten af perioperativ s\u00f8vn- og d\u00f8gnrytme p\u00e5 det naturlige overlevelsesforl\u00f8b hos patienter, der er diagnosticeret med kolorektalkr\u00e6ft. Samtidig m\u00e5les der p\u00e5 parametre som depression, tr\u00e6thed, livskvalitet og komorbiditeter i kort-, mellem- og langtidsperioden efter diagnosetidspunktet. Studiet er et observationelt studie med inklusion af 45 patienter.<\/p><ul><li><strong>PREHAB-DK &#8211;<\/strong>\u00a0<strong>Klar til Kirurgi<\/strong><\/li><\/ul><p><strong>Projektledelse:<\/strong> <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/rasmus-bojesen\/\">Rasmus Dahlin Bojesen<\/a>, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ismail-gogenur\/\">Ismail G\u00f6genur<\/a><\/p><p><strong>Status:<\/strong>\u00a0Start: marts 2018. Igangv\u00e6rende.<\/p><p><strong>Beskrivelse:<\/strong> Form\u00e5let med studiet er at unders\u00f8ge effekten af 4 ugers pr\u00e6habilitering f\u00f8r en planlagt operation for colon cancer. De m\u00e5lte parametre er b\u00e5de psykologiske, immunologiske og kliniske. Studiet er et randomiseret studie med inklusion af 48 patienter.\u00a0\u00a0\u00a0<\/p><ul><li><strong>NECT &#8211;<\/strong>\u00a0<strong>Endoskopisk assisteret elektrokemoterapi som till\u00e6g til neoadjuverende behandling af lokalt fremskreden endetarmskr\u00e6ft \u2013 et randomiseret klinisk fase II-fors\u00f8g.<\/strong><\/li><\/ul><p><strong>Registreringsnummer:<\/strong> <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03040180?cond=electrochemotherapy&amp;rank=2\">NCT03040180<\/a><\/p><p><strong>Projektledelse:<\/strong> <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/rasmus-vogelsang\/\">Rasmus Peuliche Vogelsang<\/a>, Julie Gehl, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ismail-gogenur\/\">Ismail G\u00f6genur<\/a><\/p><p><strong>Status:<\/strong> Start: januar 2017. Igangv\u00e6rende.<\/p><p><strong>Beskrivelse:<\/strong> Form\u00e5let med studiet er at unders\u00f8ge sikkerheden og effekten af neoadjuverende endoskopisk elektrokemoterapi (ECT) som till\u00e6g til neoadjuverende kemostr\u00e5leterapi (nCRT) til patienter med lokalavanceret rektumcancer. Det prim\u00e6re effektm\u00e5l er tumorregression if\u00f8lge Mandard  klassifikation. Sikkerheden evalueres med behandlingsrelaterede bivirkninger (CTCAE version 4.0). Sekund\u00e6re effektm\u00e5l er \u00e6ndringer i tumormikromilj\u00f8 bestemt med immunhistokemisk farvning og tumorregression bestemt ved hybrid PET\/MRI. Studiet er et randomiseret fase II-studie med inklusion af 40 patienter diagnosticeret med lokalavanceret rektumcancer og med planlagt neoadjuverende kemostr\u00e5leterapi inden intenderet kurativ kirurgi. Patienterne randomiseres 1:1 til nCRT  + ECT (bleomycin) vs. nCRT + kirurgi.\u00a0\u00a0\u00a0<strong>\u00a0<\/strong><\/p><ul><li><strong>Calcium elektroporation ved tidlig kolorektalcancer<\/strong><\/li><\/ul><p><strong>Registreringsnummer: <\/strong><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03694080?cond=calcium+electroporation&amp;rank=2\">NCT03694080<\/a><\/p><p><strong>Projektledelse:<\/strong> Malene Broholm Andersen, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/rasmus-vogelsang\/\">Rasmus Peuliche Vogelsang<\/a>, Julie Gehl, <a href=\"https:\/\/centerforsurgicalscience.dk\/en\/team\/ismail-gogenur\/\">Ismail G\u00f6genur<\/a><\/p><p><strong>Status:<\/strong> Start: 1 October 2018. End: 1 May 2019. Ongoing.<\/p><p><strong>Beskrivelse:<\/strong> Form\u00e5let med dette studie er at unders\u00f8ge sikkerheden og effekten af calcium elektroporation som en down-staging og immunresponderende behandling af patienter med histologisk verificeret tidlig rektum- eller sigmoideumcancer uden indikation for neoadjuverende kemostr\u00e5leterapi (eksperimental eller standard) f\u00f8r intenderet kurativ kirurgi. Studiet er et fase I eksplorativt studie med inklusion af 24 patienter \u2013 12 patienter med rektumcancer og 12 patienter med sigmoideumcancer. Sikkerheden (prim\u00e6r effektm\u00e5l) evalueres ved behandlingsrelaterede bivirkninger (CTCAE version 4.0). Sekund\u00e6re effektm\u00e5l er tumorregression, \u00e6ndringer i tumormikromilj\u00f8et bestemt med immunhistokemisk farvning \u00e6ndringer i genekspressionsprofil m\u00e5lt i perif\u00e6rt fuldblod, evaluering af det metastatiske potentiale bestemt ved cytokinprofilering og celleadh\u00e6sions- og migrationsassays.\u00a0<\/p><ul><li><strong>Calcium elektroporation for behandling af kolorektal cancer<\/strong><\/li><\/ul><p><strong>Registreringsnummer: <\/strong><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03542214?cond=calcium+electroporation&amp;rank=4\">NCT03542214<\/a><\/p><p><strong>Projektledelse:<\/strong> Malene Broholm Andersen, Julie Gehl<\/p><p><strong>Status:<\/strong> Start: maj 2018. Igangv\u00e6rende.<\/p><p><strong>Beskrivelse: <\/strong>Form\u00e5let med studiet er at unders\u00f8ge sikkerhed og respons af calcium elektroporation p\u00e5 patienter med inoperable kolorektalcancer. Totalt inkluderes 6 patienter, der alle er blevet tilbudt standardbehandling og alle godkendte behandlingsmuligheder, f\u00f8r de indg\u00e5r i studiet. Behandling med calcium elektroporation vil ikke blive sammenlignet med andre behandlinger. Alle patienter behandles \u00e9n gang, men ses der tilbagev\u00e6rende tumorv\u00e6v ved opf\u00f8lgning, og sk\u00f8nner investigator, at det er sikkert, vil patienterne blive tilbudt genbehandling op til maksimalt 3 behandlinger med 4 ugers mellemrum. Patienterne vil blive fulgt med opf\u00f8lgende unders\u00f8gelser i 12 m\u00e5neder efter f\u00f8rste behandling. Det prim\u00e6re behandlingsm\u00e5l er sikkerhed via registrering af behandlingsbivirkninger (CTCAE version 4.0). Sekund\u00e6re effektm\u00e5l er lokal tumorrespons bestemt ved immunhistokemisk farvning, systemisk respons bestemmes ved helblods-genekspressionsanalyse, multiplex cytokinassays og det metastatiske potentiale ved cytokinprofilering, celleadh\u00e6sions- og migrationsassays. Tumor burden bestemmes ved cirkulerende tumor DNA. Tumorrespons bestemmes ved CT-skanninger og RECIST-kriterier.<\/p><ul><li><strong>CISMO<\/strong><\/li><\/ul><p><strong>Projektledelse:<\/strong> Malene Broholm Andersen, Ismail G\u00f6genur<\/p><p><strong>Registreringsnummer: <\/strong>NCT03546569<\/p><p><strong>Status:<\/strong> Start: Maj 2018 Slut: Juni 2021. Igangv\u00e6rende.<\/p><p><strong>Beskrivelse: <\/strong>Dette studie har til form\u00e5l at unders\u00f8ge p\u00e5virkning af cirkulerende tumor DNA, samt immunforsvarets reaktion i forbindelse med selvudvidende stent i tyktarmen for akutstop i tarmforl\u00f8bet, grundet en kr\u00e6ftknude. Studiet inkluderer 20 patienter, der f\u00e5r taget blodpr\u00f8ver lige anl\u00e6ggelse af stent samt 1, 4 og 24 timer efter proceduren. Blodpr\u00f8ver vil blive analyseret for cirkulerende tumor DNA og cellefrit DNA. Cytokiner og chemokiner vil blive analyseret ved et immuno-oncology panel. Herudover vil der blive foretaget cellelinie fors\u00f8g til bestemmelse af adh\u00e6sion, proliferation og migration.<\/p><ul><li><strong>\u00c6ndringer I genekspression som f\u00f8lge af selvekspanderende stent som behandling inden kirurgi<\/strong><\/li><\/ul><p><strong>Projektledelse:<\/strong> Malene Broholm Andersen, Ismail G\u00f6genur<\/p><p><strong>Status:<\/strong> Start: Januar 2020 Slut: Februar 2021. Igangv\u00e6rende.<\/p><p><strong>Beskrivelse: <\/strong>Dette studie har til form\u00e5l at unders\u00f8ge p\u00e5virkning af genekspression i kr\u00e6ftv\u00e6v i forbindelse med selvudvidende stent i tyktarmen for akutstop grundet en kr\u00e6ftknude. Der vil blive indhentet biopsi fra f\u00f8r stentanl\u00e6ggelse samt v\u00e6v fra den stentede og fjernede kr\u00e6ftknude. Herved kan man sammenligne kr\u00e6ftknudens mikromilj\u00f8 f\u00f8r og efter stentanl\u00e6ggelse. \u00c6ndringer i genekspression vil blive analyseret ved NanoString teknologien. Vi benytter \u201dPanCancer IO 360 gene expression panel\u201d til messengerRNA. Dette panel inkluderer 770 kendte gener, som d\u00e6kker over sammenspillet mellem kr\u00e6ftknude, mikromilj\u00f8 og immunrespons.<\/p><ul><li><strong>Elektrokemoterapi til behandling af uhelbredelig mavekr\u00e6ft<\/strong><\/li><\/ul><p><strong>Projektledelse:<\/strong> Malene Broholm Andersen, Ismail G\u00f6genur<\/p><p><strong>Status:<\/strong> Start: Oktober 2019 Slut: Oktober 2022. Igangv\u00e6rende.<\/p><p><strong>Beskrivelse:<\/strong>Fors\u00f8get har til form\u00e5l, at unders\u00f8ge sikkerheden ved elektrokemoterapi til behandling af uhelbredelig mavekr\u00e6ft. Vi planl\u00e6gger at inkludere 8 fors\u00f8gspersoner i studiet. Fors\u00f8get vil blive udf\u00f8rt p\u00e5 to centre, Kirurgisk afdeling, Sj\u00e6llands Universitetshospital og Kirurgisk Afdeling, Odense Universitetshopital. Fors\u00f8gspersonerne vil modtage behandlingen en gang som till\u00e6g til standardbehandlingen. Dette vil foreg\u00e5 p\u00e5 Sj\u00e6llands Universitetshospital. Efterf\u00f8lgende vil de blive fulgt op ved to kontrolbes\u00f8g p\u00e5 Odense Universitetshospital eller Sj\u00e6llands Universitetshospital, 4-6 uger samt 8-12 uger efter behandlingen. Ved kontrolbes\u00f8g vil der blive udf\u00f8rt en gastroskopi med biopsi, endoskopisk ultralyd samt sp\u00f8rgeskema.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Insights into the molecular and cellular patterns of disease is currently produced at an unpreceded pace. However, the translation of basic research findings into better patient care remains a difficult but important challenge. 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