{"id":14381,"date":"2025-03-04T13:22:27","date_gmt":"2025-03-04T11:22:27","guid":{"rendered":"https:\/\/centerforsurgicalscience.dk\/?page_id=14381"},"modified":"2025-03-10T15:10:24","modified_gmt":"2025-03-10T13:10:24","slug":"ultrasound-projects","status":"publish","type":"page","link":"https:\/\/centerforsurgicalscience.dk\/da\/ultrasound-projects\/","title":{"rendered":"Ultrasound projects"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"14381\" class=\"elementor elementor-14381\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-eab9073 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"eab9073\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b2ab5b2\" data-id=\"b2ab5b2\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a0e6f9f elementor-widget elementor-widget-spacer\" data-id=\"a0e6f9f\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5abcc49 elementor-widget elementor-widget-heading\" data-id=\"5abcc49\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">ULTRASOUND \nPROJECTS<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a9c328a elementor-widget elementor-widget-spacer\" data-id=\"a9c328a\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6aa1d6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a6aa1d6\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b819f66\" data-id=\"b819f66\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-048f2b1 elementor-widget elementor-widget-spacer\" data-id=\"048f2b1\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ef13491 elementor-widget elementor-widget-image\" data-id=\"ef13491\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"504\" height=\"512\" src=\"https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2025\/03\/Ultrasound-504x512.png\" class=\"attachment-beclinic-author-avatar size-beclinic-author-avatar wp-image-14335\" alt=\"\" srcset=\"https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2025\/03\/Ultrasound-504x512.png 504w, https:\/\/centerforsurgicalscience.dk\/wp-content\/uploads\/2025\/03\/Ultrasound-12x12.png 12w\" sizes=\"(max-width: 504px) 100vw, 504px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-777630b elementor-widget elementor-widget-spacer\" data-id=\"777630b\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-001170d elementor-widget elementor-widget-spacer\" data-id=\"001170d\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2011743 elementor-widget elementor-widget-accordion\" data-id=\"2011743\" data-element_type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-accordion\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-3361\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-3361\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Stand-alone effect of CEUS sonoporation for colorectal liver metastasis measured by translational research approaches<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-3361\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-3361\"><p><strong>PI:<\/strong>Professor<a href=\"https:\/\/centerforsurgicalscience.dk\/da\/christian-pallson-nolsoe\/\"> Christian Nols\u00f8e<\/a><strong><br \/><br \/>Aim<\/strong>: This study investigates the feasibility and biological impact of contrast-enhanced ultrasound (CEUS) combined with sonoporation for colorectal liver metastases (CLM). Using translational research, we aim to assess CEUS-mediated sonoporation\u2019s effects on tumor biology, including RNA sequencing and immune response analysis, to evaluate its potential for enhancing targeted cancer treatment.<\/p><p>\u00a0<\/p><p><strong>Status:<\/strong> The project officially started on March 1, 2025, following received funding from Novo Nordisk. PhD student Maja M\u00f8nster Jeppesen is part of the project.<\/p><p>\u00a0<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-3362\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"button\" aria-controls=\"elementor-tab-content-3362\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Reducing Social Inequality through Ultrasound-Based Prevention and Early Detection of Gastrointestinal Disorders \u2013 A Path to More Healthy Life Years<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-3362\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"region\" aria-labelledby=\"elementor-tab-title-3362\"><p class=\"cvGsUA direction-ltr align-start para-style-title\"><strong><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">PI\/Investigator: <\/span><\/strong><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Professor <a href=\"https:\/\/centerforsurgicalscience.dk\/da\/christian-pallson-nolsoe\/\">Christian Nols\u00f8e<\/a><\/span><\/p><p><strong>Aim:<\/strong>This project aims to reduce social inequality in health by improving access to rapid diagnostics for patients in underserved areas with limited transportation options. By establishing a decentralized ultrasound function and integrating \u2018Fast Track Surgical Ultrasound\u2019 into the surgical outpatient clinic, the project seeks to:<\/p><ul><li>Ensure faster and more accessible diagnostics for patients in the Nyk\u00f8bing Falster catchment area.<\/li><li>Improve patient pathways by enabling direct referral for surgery without unnecessary delays.<\/li><li>Alleviate the burden on patients and relatives caused by time-consuming and resource-intensive transportation.<\/li><li>Reduce regional healthcare expenditures related to patient transport.<\/li><li>Evaluate the clinical and economic impact of expedited diagnostics on patient pathways and healthcare costs.<\/li><li>Prevent the progression of severe disease through earlier diagnosis and treatment.<\/li><\/ul><p>Additionally, the project includes a systematic research component, where the clinical and economic effects of the initiative will be scientifically evaluated through cost-benefit analyses, waiting time assessments, and documentation of improved patient pathways.<\/p><p>A subsequent PhD project will investigate the impact of decentralized healthcare services on social inequality in health, patient-perceived benefits of reduced transport and faster diagnostics, the health economic consequences of a decentralized model, and the potential for preventing disease progression through earlier intervention. The research component will include patient data collection, qualitative interviews, and analyses of logistical and economic aspects, contributing to the scientific documentation and dissemination of the project\u2019s outcomes.<\/p><p><strong>Status:<\/strong> Funding applications have been submitted to various foundations. Initially, the project will be led and conducted by Bettina Holde J\u00f8rgensen and Charlotte Feveile-Mortensen from Team Nols\u00f8e. In the long term, the plan is to recruit a PhD student to further advance the project.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-3363\" class=\"elementor-tab-title\" data-tab=\"3\" role=\"button\" aria-controls=\"elementor-tab-content-3363\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Peroperative ultrasonography in minimally invasive surgery for Crohns Disease<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-3363\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"region\" aria-labelledby=\"elementor-tab-title-3363\"><p class=\"cvGsUA direction-ltr align-start para-style-title\"><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\"><strong>PI\/Investigator<\/strong>: Professor <a href=\"https:\/\/centerforsurgicalscience.dk\/da\/christian-pallson-nolsoe\/\">Christian Nols\u00f8e<\/a><\/span><\/p><p><strong>Aim:<\/strong> This study aims to evaluate the feasibility of intraoperative intracorporeal bowel ultrasound as a supplemental tool in laparoscopic and robotic-assisted surgery for Crohn\u2019s disease (CD). Given the loss of tactile feedback in minimally invasive procedures, we hypothesize that intracorporeal ultrasound can aid in assessing disease extent, optimizing resection margins, and improving surgical decision-making. This single-center feasibility study will assess the technical and practical implementation of this approach, including its impact on surgical workflow and potential benefits in bowel-sparing strategies.<\/p><p><strong>Status:<\/strong> The project has started and is ongoing but will be put on hold for a period due to PhD Marie H\u00f8ygaard Larsen&#8217;s maternity leave. Expected restart in February 2026.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-3364\" class=\"elementor-tab-title\" data-tab=\"4\" role=\"button\" aria-controls=\"elementor-tab-content-3364\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Development of an Ultrasound Curriculum for Danish General Surgeons<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-3364\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"region\" aria-labelledby=\"elementor-tab-title-3364\"><p class=\"cvGsUA direction-ltr align-start para-style-title\"><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\"><strong>PI\/Investigator<\/strong>: Professor <a href=\"https:\/\/centerforsurgicalscience.dk\/da\/christian-pallson-nolsoe\/\">Christian Nols\u00f8e<\/a><\/span><\/p><p><strong>Aim<\/strong>: 1. To evaluate the current evidence on the clinical utility and outcomes of POCUS in abdominal surgery.<\/p><ol start=\"2\"><li>To identify gaps in knowledge and future directions for integrating POCUS into surgical practice.<\/li><\/ol><p><strong>Status<\/strong>: The project is expected to commence in late 2025 with PhD student Oliver Wedel Fischer. Funding applications have been submitted to various foundations.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ab1aec4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ab1aec4\" data-element_type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-dce7bd5\" data-id=\"dce7bd5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>ULTRASOUND PROJECTS Stand-alone effect of CEUS sonoporation for colorectal liver metastasis measured by translational research approaches PI:Professor Christian Nols\u00f8e Aim: This study investigates the feasibility and biological impact of contrast-enhanced ultrasound (CEUS) combined with sonoporation for colorectal liver metastases (CLM). Using translational research, we aim to assess CEUS-mediated sonoporation\u2019s effects on tumor biology, including RNA &hellip;<\/p>","protected":false},"author":10,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Ultrasound projects - Center for Surgical Science (CSS)<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/centerforsurgicalscience.dk\/da\/ultrasound-projects\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ultrasound projects - Center for Surgical Science (CSS)\" \/>\n<meta property=\"og:description\" content=\"ULTRASOUND PROJECTS Stand-alone effect of CEUS sonoporation for colorectal liver metastasis measured by translational research approaches PI:Professor Christian Nols\u00f8e Aim: This study investigates the feasibility and biological impact of contrast-enhanced ultrasound (CEUS) combined with sonoporation for colorectal liver metastases (CLM). 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